GHiGS

Global Health in the Global South

Details

Centre de recherche INSERM U1219
Université de Bordeaux – ISPED Case 11
146 rue Léo-Saignat
33076 BORDEAUX cedex

Tél : 05 57 57 15 80

Tél : 05 57 57 92 40

Contact

Gwenaëlle Clouet

Elodie Rabourdin

Dr Olivier Marcy
MD, PhD, GHIGS Director

Olivier Marcy is a clinical epidemiologist and researcher at the University of Bordeaux and research director at IRD (French Institute for Research and Sustainable Development).

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Dr Renaud Becquet
PHD, GHiGS Deputy director

Renaud BECQUET, senior scientist at Inserm, has a PhD and a HDR in epidemiology (University of Bordeaux).

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Informations Publications

Objectives

The objectives of the GHiGS team are:

to produce data on diseases affecting the global south, their epidemiology, risk factors and consequences;
to use these findings to design and to evaluate innovative interventions at individual and population level, which are effective, but also equitable and sustainable, and contribute to the advancement of global health.

Per the definition of Koplan et al. (The Lancet 2009;373(9679):1993-5), global health is an area for study, research, and practice that places a priority on improving health and achieving equity in health for all people worldwide. Global health emphasizes transnational health issues, determinants, and solutions; involves many disciplines within and beyond the health sciences and promotes interdisciplinary collaboration; and is a synthesis of population-based prevention with individual-level clinical care.

Per the definition of the World Bank, the global south is made up of Africa, Latin America and the Caribbean, Pacific Islands, and the developing countries in Asia, including the Middle East.

Research areas

Scientific orientations of the research team

The GHiGS team aims to contribute to improving health at individual and population level in countries from the Global South and to contribute to reducing health inequities between countries, as well as within countries.

Low- and middle-income countries, and in particular in Sub-Saharan Africa, are going through major changes including epidemiologic, sociodemographic, economic, agronomic, technological, and climatic transitions. At the same time, they are carrying the triple burden of: (i) infectious diseases, including HIV, tuberculosis, malaria, hepatitis and a number of other emerging infectious disease threats (including hemorrhagic fevers and other epidemics); (ii) growingly prevalent non-communicable diseases (NCDs; diabetes, cancers, hypertension, obesity), and (iii) unprecedented outdoor pollutions and environmental threats. The GHiGS team aims to respond to these major transitions and new challenges through integrated, multi-level and inter-disciplinary research approaches in the context of the Global South.

Among the key highlights of the past five years, the GHiGS team contributed to a major revision in the international HIV treatment guidelines issued by the World Health Organization and was among the rare research teams worldwide having conducted a treatment trial to reduce mortality during the Ebola virus disease epidemic in West Africa.

In the coming years, the GHiGS team will strengthen and expand two key research themes, i.e. infectious diseases and mother and child health issues, to address new challenges in the field of diagnosis, care, and treatment and beyond.

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Research areas

Scientific orientations of the research team

NCD research, previously addressed by the team in relation with infectious diseases (HPV and HBV related cancers, cardiovascular and metabolic HIV-comorbidities), will become a standalone research theme. Major challenges in implementing evidence-based interventions will be addressed within a cross-sectional and structural research axis on “Models of care, implementation and health systems”. Finally, beyond individual and health systems levels, the GHiGS team will explore the impact on health (NCDs, emerging epidemics,..) of global forces and environmental changes (climate change, bacterial ecosystem, resistance to antimicrobials, pollution…), as part of the “People in their environment” axis.

Research in the GHiGS team will be built on equal partnership and co-construction with scientific partners, clinicians, policy-makers from Global South countries.

Through its expanded research program and strengthened and expanded collaborations and partnerships, the ambition of the GHiGS team is to contribute to the achievement of the Sustainable Development Goal #3 on Health and Well-Being.

Structuration of the research team

The GHiGS activities will be organized around 3 research themes (infectious diseases; maternal and child health; non-communicable diseases) which correspond to major global health challenges; and 3 cross-sectional axes (Prevention, diagnosis and treatment; models of care, implementation, and health systems; people in their environment) that will structure research efforts, collaborations, and development of methods and scientific engineering capacities.

Key Publications 2023

Alidou S, Dahourou LD, Dah TTE, Sogo A, Kenao TS, Yehadji D, Meda N, Ekouevi DK. Unmet needs for modern contraceptive methods among sexually active adolescents and young women in Togo: a nationwide cross-sectional study. Front Public Health. 2023;11:1169180. https://doi.org/10.3389/fpubh.2023.1169180

Arikawa S, Tchankoni MK, Gbeasor-Komlanvi FA, Atekpe SP, Atcha-Oubou T, Figueroa-Romero A, Fombah AE, Saute F, Samai M, Menendez C, Gonzalez R, Briand V, Ekouevi DK, consortium M. Prevalence and risk factors associated with malaria infection in children under two years of age in southern Togo prior to perennial malaria chemoprevention implementation. Malar J. 2023;22(1):357. https://doi.org/10.1186/s12936-023-04793-y

Bernard C, Font H, Diallo Z, Ahonon R, Tine JM, Abouo FNG, Tanon A, Messou E, Seydi M, Dabis F, Dartigues J-F, de Rekeneire N. Factors associated with verbal fluency in older adults living with HIV in West Africa: A longitudinal study. Trop Med Int Health. 2023;28(1):35-42. https://doi.org/10.1111/tmi.13830

Boni SP, Horo A, Didi-Kouko-Coulibaly J, Tanon A, Tchounga BK, Coffie PA, Comoe J-C, Moh RD, Dabis F, Adoubi I, Jaquet A, IeDEA West Africa Collaboration. Impact of HIV infection on access to cancer care and survival among women with invasive cervical cancer in Cote d’Ivoire: A prospective cohort study. Int J Gynaecol Obstet. 2023;163(2):392-401. https://doi.org/10.1002/ijgo.14925

Cazes C, Phelan K, Hubert V, Boubacar H, Bozama LI, Sakubu GT, Senge BB, Baya N, Alitanou R, Kouame A, Yao C, Gabillard D, Daures M, Augier A, Anglaret X, Kinda M, Shepherd S, Becquet R. Optimising the dosage of ready-to-use therapeutic food in children with uncomplicated severe acute malnutrition in the Democratic Republic of the Congo: a non-inferiority, randomised controlled trial. EClinicalMedicine. 2023;58:101878. https://doi.org/10.1016/j.eclinm.2023.101878

De Castro N, Chazallon C, Brites C, Messou E, Khosa C, Laureillard D, Chau GD, Pilotto JH, Eholie S, Delaugerre C, Molina J-M, Wittkop L, Grinsztejn B, Marcy O. Virologic response to antiretroviral therapy in people with HIV and tuberculosis in high tuberculosis burden countries. AIDS. 2023;37(12):1837-42. https://doi.org/10.1097/qad.0000000000003521Joshi B, De Lima YV, Massom DM, Kaing S, Banga M-F, Kamara ET, Sesay S, Borand L, Taguebue J-V, Moh R, Khosa C, Breton G, Mwanga-Amumpaire J, Bonnet M, Wobudeya E, Marcy O, Orne-Gliemann J, group TB-SDs. Acceptability of decentralizing childhood tuberculosis diagnosis in low-income countries with high tuberculosis incidence: Experiences and perceptions from health care workers in Sub-Saharan Africa and South-East Asia. PLOS Glob Public Health. 2023;3(10):e0001525. https://doi.org/10.1371/journal.pgph.0001525

Marcy O, Wobudeya E, Font H, Vessiere A, Chabala C, Khosa C, Taguebue J-V, Moh R, Mwanga-Amumpaire J, Lounnas M, Mulenga V, Mavale S, Chilundo J, Rego D, Nduna B, Shankalala P, Chirwa U, De Lauzanne A, Dim B, Tiogouo Ngouana E, Folquet Amorrissani M, Cisse L, Amon Tanoh Dick F, Komena EA, Kwedi Nolna S, Businge G, Natukunda N, Cumbe S, Mbekeka P, Kim A, Kheang C, Pol S, Maleche-Obimbo E, Seddon JA, Mao TE, Graham SM, Delacourt C, Borand L, Bonnet M. Effect of systematic tuberculosis detection on mortality in young children with severe pneumonia in countries with high incidence of tuberculosis: a stepped-wedge cluster-randomised trial. Lancet Infect Dis. 2023;23(3):341-51. https://doi.org/10.1016/s1473-3099(22)00668-5

Phelan K, Seri B, Daures M, Yao C, Alitanou R, Aly AAM, Maidadji O, Sanoussi A, Mahamadou A, Cazes C, Moh R, Becquet R, Shepherd S. Treatment outcomes and associated factors for hospitalization of children treated for acute malnutrition under the OptiMA simplified protocol: a prospective observational cohort in rural Niger. Front Public Health. 2023;11:1199036. https://doi.org/10.3389/fpubh.2023.1199036

Plazy M, Doucet M-H, Timbo Songbono C, Sanon A, Issiaka B, Martin C, Da I, L’hostellier A, Marcy O, Malvy D, Poda A, Delamou A, Berthe A, Orne-Gliemann J. Acceptability and feasibility of home and hospital follow-up in Burkina Faso and Guinea: A mixed-method study among patients of the COVID-19 Coverage-Africa clinical trial. PLOS Glob Public Health. 2023;3(7):e0001545. https://doi.org/10.1371/journal.pgph.0001545

View all of the team’s publications in Oskar

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Posted on : 02 Feb 2023

IPORA (Interdisciplinary Policy-Oriented Research on Africa) agreement signed in Abidjan, Côte d'Ivoire

Events

Le Projet “Interdisciplinary Policy-Oriented Research on Africa” (IPORA) est un des 7 Grands Projets de Recherche (GPR) de l’Université de Bordeaux. L’accord de consortium a été signé ce mardi 24 janvier 2023 à Abidjan, Côte d’Ivoire. Contact : Ida Viho – ida.viho@u-bordeaux.fr Le projet IPORA reunit 4 Universités : l’Université de Bordeaux (France), l’Université Félix Houphouët-Boigny d’Abidjan […]

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