11-22-2017 / 12h-13h — Exposure misclassification in environmental epigenetic studies: is DNA-methylation a mediator or a biomarker?
SeminarsInvited by Hélène Jacqmin-Gadda – BIOSTATISTICS TEAM Assessing whether epigenetic alterations mediate associations between environmental exposures and health outcomes is increasingly popular. We investigate the impact of exposure misclassification in such investigations.We quantify bias and false positive rates due to exposure misclassification in mediation analysis and assess the performance of SIMEX correction approach. Further, we […]