Launch of the ANR BIOMAC project on blood biomarkers for age-related macular degeneration
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Fleur CHAUMET, Barbara LE BOT, Cécile DELCOURT, Niyazi ACAR – Launch meeting on 02/01/2024 in Paris
Launch of the ANR BIOMAC project
on blood biomarkers for age-related macular degeneration
With the support of the ANR, the LEHA team is launching the BIOMAC project on blood biomarkers for age-related macular degeneration, coordinated by Cécile Delcourt.
Age-related macular degeneration (AMD) is a major cause of blindness. In addition to aging and genetic susceptibility, nutrition and smoking are major drivers of this complex disease.
The main objectives of this project are :
1) to develop and validate a combination of blood nutritional and smoking biomarkers strongly associated with progression to advanced AMD;
2) to determine whether this combination of biomarkers can improve the predictive performance of a multidimensional model;
3) to investigate the associations of these blood biomarkers with cutting-edge retinal imaging biomarkers.
In the future, the identified biomarkers will represent a major asset for the development of personalized preventive strategies, helping to target, tailor and monitor lifestyle interventions.
This project is coordinated by Cecile Delcourt, in collaboration with CSGA-Inrae (Dijon) and LERES-EHESP (Rennes) and was awarded a grant by the National Research Agency (ANR) in July 2023.