2023-… deputy director of the BIOSTAT research team, Inserm BPH, Bordeaux, France.
2019-… Director of Research, Inserm, Bordeaux, France.
2008-2019 Researcher, Inserm, Bordeaux, France.
2008 Research Assistant, Biostatistics and Nutrition departments, Inserm, Bordeaux, France.
2008 Assistant Professor, ISPED, Université Bordeaux Segalen, Bordeaux, France.
2007 Postdoctoral fellow, Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, USA.
2003-2006 Assistant professor, ISPED, Université Bordeaux Segalen, Bordeaux, France.
2014 HDR (Habilitation to conduct research), Univ. Bordeaux, France.
2006 PhD in Biostatistics, Univ. Bordeaux Segalen, France.
2003 Master degree in Epidemiology and Public Health, ISPED, Univ. Bordeaux Segalen, France.
2002 Master degree in Biostatistics, National School for Statistics and Information Analysis, ENSAI, Rennes, France.
Development of statistical methods to describe, explain and predict chronic disease progressions.
I specialized in the joint analysis of correlated longitudinal markers and event time history with applications mainly in neuro-degenerative diseases (e.g., Alzheimer’s disease, Multiple System Atrophy) and cancers. My works most often involve latent processes to translate dynamic health phenomena measured by repeated noisy variables, as well as random effects and latent classes to translate the heterogeneity of disease progression.
My research is highly motivated by epidemiological and clinical questions thanks to strong collaborations with epidemiologists and clinicians, and access to large cohort studies. It covers a wide range of statistical topics, from causal inference to dynamic prediction techniques, always with an emphasis on data challenges and modeling solutions coming from biostatistics with openings to machine learning and psychometrics.
The developments of my research group are made available in R packages with constant maintainance and upgrades
Joint models, Latent class mixed models, Latent variable models, (Generalized) linear mixed models, Longitudinal analysis of psychometric scales in Masters, summer schools, short courses
I serve as Associate Editor for Biometrics (since 2014) and I am a former Associate Editor of Biostatistics (2016-2022).
I belong to the leadership committee of the MELODEM initiative (Methods in Longitudinal Research in Dementia). http://melodem.org/
I am part of the STRATOS initiative (STRengthening Analytical Thinking for Observational Studies), topic group Measurement Error and Misclassification since 2022. https://stratos-initiative.org/
I am a member of the Representative Council of the International Biometric Society (IBS) and of the Council of the French Biometric Society (SFB).
See on WOS: https://www.webofscience.com/wos/author/record/1208723
or ORCID: https://orcid.org/0000-0002-9884-955X
For pre-prints, see Arxiv page: http://arxiv.org/a/proustlima_c_1
lcmm: Extended Mixed Models Using Latent Classes and Latent Processes. R package: https://cecileproust-lima.github.io/lcmm/
DynForest: Random Forest with Multivariate Longitudinal Predictors. R package https://github.com/anthonydevaux/DynForest
hdlandmark: landmark approach for dynamic prediction of time-to-events from large dimensional longitudinal biomarker history. R package; https://github.com/anthonydevaux/hdlandmark
marqLevAlg: A Parallelized Algorithm for Least-Squares Curve Fitting. R package; https://github.com/VivianePhilipps/marqLevAlgParallel
JLPM: Joint models based on Latent Processes. R package; https://github.com/VivianePhilipps/JLPM
CInNPL: Causal Inference in a Network of Latent Processes. R package; https://github.com/bachirtadde/CInLPN
NormPsy: Normalisation of Psychometric Tests. R package
See my github repository at https://github.com/CecileProust-Lima
2024 Continuous-time latent variable modeling of measurement scales in health studies
2024 Analysis of multivariate longitudinal and survival data: from joint models to random forests – updated
2023 Analysis of multivariate longitudinal and survival data: from joint models to random forests
2023 Correctly accounting for misclassification when linking latent groups with external variables
2023 How to include time-varying exposures prone to measurement error in survival analyses?
2022 Joint Models based on Latent Classes and Latent Processes using lcmm R package
2021 Joint modelling of multivariate markers measured repeatedly over time and clinical endpoints
